Manchester United have a few injury issues to deal with at the moment with Rasmus Hojlund, Luke Shaw, Mason Mount, Victor Lindelof, Tyrell Malacia and Leny Yoro all out of action. The Red Devils are keen to return to winning ways after losing two of their first three fixtures of the new Premier League.
They lost 3-0 at home to Liverpool last time out before the international and will be eager to beat newly promoted Southampton away this weekend to avoid more pressure mounting on Erik ten Hag. Here is a look at the predicted starting XI for United against the Saints...

1. GK: Andre Onana
The goalkeeper should keep his place between the sticks as usual for Manchester United. | Getty Images Photo: Getty Images

2. RB: Noussair Mazraoui
The Red Devils swooped to sign last month from Bayern Munich. | Manchester United via Getty Images Photo: Manchester United via Getty Images

3. CB: Matthijs de Ligt
The Dutchman reunited with Erik ten Hag in the summer transfer window. | Getty Images Photo: Getty Images

4. CB: Lisandro Martinez
The 26-year-old has been playing his football at Old Trafford since 2022. | Getty Images Photo: Getty Images