Manchester United have a few injury issues to deal with at the moment with Rasmus Hojlund, Luke Shaw, Mason Mount, Victor Lindelof, Tyrell Malacia and Leny Yoro all out of action. The Red Devils are keen to return to winning ways after losing two of their first three fixtures of the new Premier League.
They lost 3-0 at home to Liverpool last time out before the international and will be eager to beat newly promoted Southampton away this weekend to avoid more pressure mounting on Erik ten Hag. Here is a look at the predicted starting XI for United against the Saints...

5. LB - Diogo Dalot
He is having to slot in left-back with Luke Shaw and Tyrell Malacia out of action. | AFP via Getty Images Photo: AFP via Getty Images

6. CDM: Kobbie Mainoo
The youngster has a big part to play for the Red Devils this season. | Manchester United via Getty Images Photo: Manchester United via Getty Images

7. CDM: Manuel Ugarte
Casemiro's struggles could open the door for the new boy to start from the off. | Manchester United via Getty Images Photo: Manchester United via Getty Images

8. RW: Alejandro Garnacho
He has been playing off the right over recent times. | Getty Images Photo: Getty Images

